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Credited with MDMA's popularisation in the late 1970s and early 1980s, Shulgin also championed the treatment of depression and post-traumatic stress disorder (PTSD) through the psychopharmaceutical use of MDMA. In subsequent years, Shulgin discovered, synthesized, and bioassayed over 230 psychoactive compounds. This means he found, made and tested over 230 psychoactive compounds in vivo , or in a whole, living organism...namely, himself! In 1991 and 1997, he and his wife Ann authored the books PiHKAL and TiHKAL on the topic of psychoactive drugs. [Excerpted and adapted from Transform Press bio.]
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